Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. Non-Alcoholic Steatohepatitis (NASH) : An animal study compared a placebo group with a group given 200 mg/kg body weight silymarin for 12 weeks to two groups of rats with NASH. If you’re wondering how much milk thistle to take to improve your health, the answer depends on your individual needs. A double-blind, randomized, comparator study in 35 patients with obsessive-compulsive disorder reported similar efficacy between 8-week treatment with milk thistle extract (600 mg/day [taken as 200 mg capsules 3 times a day]) and fluoxetine (30 mg/day [taken as … A Natural Approach To Liver Health. They identified 8 randomized clinical trials that had enrolled 587 patients with NAFLD who took silymarin. The active compound in milk thistle, known as silymarin is a potent antioxidant and anti-inflammatory agent that directly impacts liver function. Clinical data. Read Time: 3 minutes Milk thistle has been a critical part of ancient medicine for over 2000 years. The product, silymarin, is an active extract of milk thistle, a plant found throughout the world. Milk thistle is promoted as a dietary supplement for hepatitis, cirrhosis, … An individual with normal health can take 140-800mg of milk thistle per day to treat fatty liver naturally. Historically, people have used milk thistle for liver disorders and gallbladder problems. Over those years, this herb picked up the nickname the liver protector. After … As an herb that’s considered a “hepatic, galactogogue, demulcent and cholagogue,” milk thistle is considered one of the most common natural supplements for liver disorders in the U.S., thanks to its many health benefits. Silybin is a component with the greatest degree of biological activity and makes up 50% to 70% of silymarin. Medical and scientific research carried out on milk thistle has shown different types of results. Milk Thistle Dosage for Fatty Liver. On the other hand, a fatty liver condition can lead to damage, including scarring of the liver. Milk thistle can be used in high doses to stimulate a natural liver detox. Milk thistle is thought to exert its protective effects on the liver through the promotion of liver cell growth and the prevention of oxidation and inflammation in the liver. Milk thistle directly targets the liver. Best Milk Thistle Supplement for Liver: Make sure the milk thistle supplement contains 80% of the herb and it has undergone proper laboratory testing. Some people might experience loose bowels for the first few days, but this will eventually pass. Today, doctors suggest milk thistle and the extract silymarin for optimal liver health. The study authors indicate that the liver's primary role predisposes individuals who develop NAFLD to other systemic metabolic disorders. Get it back in working order so it can function at optimal levels by detoxing your liver with a milk thistle flush. A milk thistle liver detox is an important step in maintaining a properly functioning liver. The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three isomer flavonolignans (silybin, silydianin, and silychristin) collectively known as silymarin. About 150 milligrams of milk thistle, taken three times daily, qualifies as a … Researchers have discovered that milk thistle inhibits the release of cytokines from the liver that normally increases with fatty liver inflammation. Milk thistle is scientifically supported enough to be a prescription medication in some areas of the world, but its actions tend to be specific to the liver, and fatty liver is not necessarily part of the purported health benefits. Over the years the liver gets bogged down by heavy metals, fatty foods, alcohol and chemicals, and becomes sluggish. 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